The journal *Nature* has published an Expression of Concern regarding the research article “Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis.” The concern stems from issues with the original publication, though specific details are not provided in this notice.
The expression of concern was published online on July 28, 2026. *Nature* identifies the paper’s DOI as 10.1038/s41586-026-10923-8. The journal has not detailed the nature of the concerns prompting this action beyond stating that they exist regarding the research presented in the article.
The original study investigated how carcinoma-produced factors activate myeloid cells through TLR2, and subsequently stimulate metastasis – the spread of cancer to other parts of the body. An Expression of Concern is a formal statement issued by a journal to alert readers to potential issues with a published paper. It falls short of retraction but indicates that concerns have been raised about the research’s validity or integrity.
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